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Author: meron
Lack of genetic evidence for a role of SLC25A46 in alpha-synucleinopathies
Yu H, Parlar SC, Senkevich K, Somerville EN, Zhang Z, Liu L, Teferra M, Ahmad J, Asayesh F, Rouleau GA and Gan-Or Z. Lack of genetic evidence for a role of SLC25A46 in alpha-synucleinopathies. Under review. 2026. Preprint, PubMed
Machine learning and burden analyses highlight novel genes in Parkinson’s Disease.
Parlar SC, Yu E, Kanagasingam S, Zhang Z, Liu L, Ghamgosar Shahkhali M, Chantereault C, Karpilovsky N, Worrall D, Thomas RA, Senkevich K, Fon EA and Gan-Or Z. Machine learning and burden analyses highlight novel genes in Parkinson’s Disease. Under review. 2026. Preprint, PubMed
Somerville EN, Liu L, Ta M, Iwaki H, Senkevich K, Alcalay RN and Gan-Or Z. Genome-wide association studies identify genetic determinants of synucleinopathy biomarkers. Under review. 2026. Preprint, PubMed
Brain size links neurodevelopment to neurodegeneration in Parkinson’s disease.
Azizi H, Abbasi N, Liu L, Pastor-Bernier A, Tremblay C, Pourmajidian M, Senkevich K, Morys F, Vo A, Moqadam R, Rajimehr R, Yu E, Savadjiev P, Markello RD, Shafiei G, Khatibi N, Jahanshad N, Thompson PM, Poline JB, Gan-Or Z, Misic B, Zeighami Y and Dagher A. Brain size links neurodevelopment to neurodegeneration in Parkinson’s disease. Under review. 2026. Preprint, PubMed
Genome-wide association study of REM-sleep behaviour disorder identifies new risk loci
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LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli.
MacDougall EJ, Chen CXQ, Deneault E, You Z, Abdian N, Durcan TM, Senkevich K, Gan-Or Z and Fon EA. LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli. Under review. 2026. Preprint, PubMed
Post-traumatic stress disorder and REM-sleep behavior disorder: exploring genetic associations and causal links
Ghamgosar Shahkhali M, Liu L, Ghamgosar Shahkhali MH, Yu E, Asayesh F, Ahmad J, Teferra M, Arnulf I, Dodet P, Ju YE, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Ibrahim A, Stefani A, Högl B, Akrtan-Süzgün M, Iranzo A, Serradell M, Montini A, Maya G, Gaig C, Luigi Gigli G, Valente M, Janes F, Bernardini A, Dauvilliers Y, Sonka K, Kemlink D, Dusek P, Sommerauer M, Tamgüney G, Figorilli M, Puligheddu M, Cochen De Cock V, Oertel W, Janzen A, Antelmi E, Mollenhauer B, Trenkwalder C, Sixel-Doring F, Terzaghi M, Fiamingo G, Skorvanek M, Kulcsarova K, Abril B, Charley Monaca C, Ferini-Strambi L, Bušková J, Orso B, Mattioli P, Arnaldi D, Dijkstra F, Viaene M, Boeve BF, Ross OA, Rouleau GA, Neilson LE, Elliott JE, Lim MM, Postuma RB, Gan-Or Z. Post-traumatic stress disorder and REM-sleep behavior disorder: exploring genetic associations and causal links. Under review. 2026. Preprint, PubMed.
Genomic structural equation modeling of impulsivity and risk-taking traits reveals three latent factors distinctly associated with brain structure and development
Shishikura M, Liu L, Yu E, Zhu R, Vilar-Ribó L, Cupertino RB, Palmer AA, Sanchez-Roige S, Vainik U, Morys F, Gan-Or Z, Misic B, Dagher A. Genomic structural equation modeling of impulsivity and risk-taking traits reveals three latent factors distinctly associated with brain structure and development. Under Review. 2026. Preprint, PubMed.
Polygenic scores for disease risk are not associated with clinical outcomes in Parkinson’s disease.
Tan MMX, Iwaki H, Bandres-Ciga S, Sosero Y, Shoai M, Brockmann K, Williams NM, Alcalay RN, Maple-Grødem J, Alves G, Tysnes OB, Auinger P, Eberly S, Heutink P, Simon DK, Kieburtz K, Hardy J, Williams-Gray CH, Grosset DG, Corvol JC, Gan-Or Z, Toft M and Pihlstrøm L. Polygenic scores for disease risk are not associated with clinical outcomes in Parkinson’s disease. Under review. 2026. Preprint, PubMed