Cressatti M, Pinilla-Monsalve GD, Blais M, Normandeau CP, Degroot C, Kathol I, Bogard S, Bendas A, Camicioli R, Dupré N, Gan-Or Z, Grimes DA, Kalia LV, MacDonald PA, McKeown MJ, Martino D, Miyasaki JM, Schlossmacher MG, Stoessl AJ, Strafella AP, Fon EA, Monchi O. Advancing Parkinson’s Disease Research in Canada: The Canadian Open Parkinson Network (C-OPN) Cohort. J Parkinsons Dis. 2024. PubMed
Category: Publications
GLON5 Frequency in idiopathic REM sleep behavior disorder: a multicenter study.
Postuma RB, Vorasoot N, St. Louis EK, Pelletier A, Lim MM, Elliott JE, Gagnon JF, Gan-Or Z, Forsberg LK, Fields JA, Ross OA, Singer W, Huddleston DE, Bliwise DL, Avidan AY, Howell MJ, Schenck CH, McLeland J, Davis AA, Criswell SR, Videnovic A, During EH, Miglis MG, Boeve BF, Ju YES, McKeon A and the North American Prodromal Synucleinopathy (NAPS) Consortium. IGLON5 Frequency in idiopathic REM sleep behavior disorder: a multicenter study. Neurol Neuroimmunol Neuroinflamm. 2024. PubMed
RAB32 Ser71Arg in autosomal dominant Parkinson’s disease: linkage, association, and functional analyses.
Gustavsson EK, Follett J, Trinh J, Barodia SK, Real R, Liu Z, Grant-Peters M, Fox JD, Cresswell S, Stoessl AJ, Rajput A, Rajput AH, Auer R, Tilney R, Sturm M, Haack TB, Lesage S, Tesson C, Brice A, Vilarino-Guell C, Ryten M, Goldberg MS, West AB, Hu MT, Morris HR, Sharma M, Gan-Or Z, Samanci B, Lis P, Tocino TP, Amouri R, Ben Sassi S, Hentati F, Tonelli F, Alessi DB and Farrer MJ. RAB32 Ser71Arg in autosomal dominant Parkinson’s disease: linkage, association, and functional analyses. Lancet Neurology. 2024. Preprint, PubMed
Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)
Chertkow H, Phillips N, Rockwood K, Anderson N, Andrew MK, Bartha R, Beaudoin C, Bélanger N, Bellec P, Belleville S, Bergman H, Best S, Bethell J, Bherer L, Black S, Borrie M, Camicioli R, Carrier J, Cashman N, Chan S, Crowshoe L, Cuello C, Dang-Vu T, Das S, Dixon RA, Ducharme S, Einstein G,Evans AC, Fahnestock M, Feldman H, Ferland G, Finger E, Fisk J, Fogarty J, Fon E, Gan-Or Z, Gauthier S, Greenwood C, Henri-Bellemare C, Herrmann N, Hogan DB, Hsiung R, Itzhak I, Jacklin K, Lanctôt K, Lim A, MacKenzie I, Masellis M, Maxwell C, McAiney C, McGilton K, McLaurin J, Mihailidis A, Mohades Z, Montero-Odasso M, Morgan D, Naglie G, Nygaard H, O’Connell M, Pilon R, Rajah MN, Rapoport M, Roach P, Robillard JM, Rogaeva E, Rosa-Neto P, Rylett J, Sadavoy J, St. George-Hyslop P, Seitz D, Smith E, Stefanovic J, Tierney M, Vedel I, Walker JD, Wellington C, Whitehead V and Wittich W. Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA). J Alzheimers Dis. 2024. PubMed
Parkinson’s risk gene CTSB promotes α-synuclein clearance and lysosome function in dopamine neurons.
Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, del Cid Pellitero, Chen CXC, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z (co-corresponding author) and Fon EA. Parkinson’s risk gene CTSB promotes α-synuclein clearance and lysosome function in dopamine neurons. Mol Neurodegener. 2024. Preprint, PubMed
Are LRRK2 p.G2019S or GBA1 variants associated with long-term outcomes of deep brain stimulation for Parkinson’s disease?
Anis S, Goldberg T, Shvueli E, Kozlov Y, Redlich Y, Lavi N, Lavie I, Sosero YL, Gan-Or Z, Ungar L, Zibly Z, Greenbaum L, Fay-Karmon T and Hassin-Baer S. Are LRRK2 p.G2019S or GBA1 variants associated with long-term outcomes of deep brain stimulation for Parkinson’s disease? Parkinsonism Relat Disord. 2024. PubMed
Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium
Elliott J, Ligman B, Bryant-Ekstrand M, Keil A, Powers K, Olivio C, Neilson L, Postuma R, Pelletier A, Gagnon JF, Gan-Or Z, Yu E, Liu L, St. Louis E, Forsberg L, Fields J, Huddleston D, Bliwise D, Avidan A, Howell M, Schenck C, McLeland J, Criswell S, Videnovic A, During E, Miglis M, Shprecher D, Lee-Iannotti J, Boeve B, Ju YE and Lim M. Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium. Sleep. 2024. PubMed
Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson′s disease.
Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia.
Sosero YL, Ferwerda B, Tocino MTP, Belloso DR, Gomez-Garre P, Faouzi J, Pavelka L, Marques TM, Gomes CPC, Kolodkin A, May P, Milanowski LM, Wszolek ZK, Uitti RJ, Heutink P, van Hilten J, Simon DK, Eberly S, Fernandez IA, Krohn L, Yu E, Freeman K, Rudakou U, Ruskey JA, Asayesh F, Menendez M, Pastor P, Ross O, Kruger R, Corvol JC, Koks S, Mir P, de Bie RMA, Iwaki H and Gan-Or Z. Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia. Movement Disorders. 2024. Preprint, PubMed
Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease.
Menon PJ, Sambin S, Criniere-Boizet B, Courtin T, Tesson C, Casse F, Ferrien M, Mariani LL, Carvalho S, Lejeune FX, Rebbah S, Martet G, Houot M, Lanore A, Mangone G, Roze E, Vidailhet M, Aasly J, Gan-Or Z, Yu E, Dauvilliers Y, Zimprich A, Tomantschger V, Pirker W, Álvarez I, Pastor P, Di Fonzo A, Bhatia KP, Magrinelli F, Houlden H, Real R, Quattrone A, Limousin P, Korlipara P, Foltynie T, Grosset D, Williams N, Narendra D, Lin HP, Jovanovic C, Svetel M, Lynch T, Gallagher A, Vandenberghe W, Gasser T, Brockmann K, Morris HR, Borsche M, Klein C, Corti O, Brice A, Lesage S and Corvol JC. Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease. npj Parkinson’s Disease. 2024. Preprint, PubMed