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Analysis of common and rare VPS13C variants in late onset Parkinson disease.

Rudakou URuskey JAKrohn L, Laurent SB, Spiegelman D, Greenbaum L, Yahalom G, Desautels A,  Montplaisir JY, Fahn S, Waters CH, Levy O, Kehoe CM, Narayan S, Dauvilliers Y, Dupré N, Hassin-Baer S, Alcalay RN, Rouleau GA, Fon EA and Gan-Or ZAnalysis of common and rare VPS13C variants in late onset Parkinson disease. Neurology Genetics.  2020. PubMedPreprint

Age at Onset of Parkinson’s Disease Among Ashkenazi Jewish Patients: Contribution of Environmental Factors, LRRK2 p.G2019S and GBA p.N370S Mutations.

Yahalom G, Rigbi A, Israeli-Korn S, Krohn LRudakou URuskey JA, Benshimol L, Tsafnat T, Gan-Or Z, Hassin-Baer S and Greenbaum L. Age at Onset of Parkinson’s Disease Among Ashkenazi Jewish Patients: Contribution of Environmental Factors, LRRK2 p.G2019S and GBA p.N370S MutationsJournal of Parkinson’s Disease. 2020. PubMed

Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson’s disease. 

Ouled Amar Bencheikh BSenkevich KRudakou UYu EMufti KRuskey JAAsayesh F, Laurent SB, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Espay AJ, Dupré N, Greenbaum L, Hassin-Baer S, Rouleau GA, Alcalay RN, Fon EA and Gan-Or Z. Variants in the Niemann-Pick type C gene NPC1 are not associated with Parkinson’s disease. Neurobiology of Aging. 2020. PubMedPreprint

Lysosomal dysfunction in Parkinson’s disease; evidence from human genetics.

Senkevich K and Gan-Or ZLysosomal dysfunction in Parkinson’s disease; evidence from human genetics. Parkinsonism and Related Disorders. 2019. Review. PubMed

No evidence for a role of variation in alcohol dehydrogenase genes in the risk for Parkinson’s disease

Kim JJ, Bandres-Ciga S, Blauwendraat C, International Parkinson’s Disease Genomics Consortium and Gan-Or ZNo evidence for a role of variation in alcohol dehydrogenase genes in the risk for Parkinson’s disease. Neurobiology of Aging. 2019. PubMedPreprint

Genetic and epidemiological characterization of restless legs syndrome in Québec.

Akçimen F, Ross JP, Sarayloo F, Liao C, Oliveira RDB, Ruskey JA, Bourassa CV, Xiong L, Dion PA, Gan-Or Z and Rouleau GA. Genetic and epidemiological characterization of restless legs syndrome in Québec. Sleep. 2019. PubMed

Makarious MB, Diez-Fairen M, Krohn L, Kia D, Blauwendraat C, Bandres-Ciga S, Ding J, Pihlstrom L, Houlden H, Scholz SW and Gan-Or ZARSA variants in a-synucleinopathies. Brain. 2019. PubMed

Exposure to pesticides and welding hastens the age-at-onset of Parkinson disease.

Gamache PL, Gan-Or Z, Lebouthiller J, Roux-Dubois N, Provencher P and Dupré N. Exposure to pesticides and welding hastens the age-at-onset of Parkinson diseaseCanadian Journal of Neurological Sciences. 2019. PubMed

SPTAN1 variants as a potential cause for autosomal recessive hereditary spastic paraplegia.

Leveille EEstiar MAKrohn L, Spiegelman D, Dionne-Laporte A, Dupré N, Trempe JF, Rouleau GA and Gan-Or ZSPTAN1 variants as a potential cause for autosomal recessive hereditary spastic paraplegiaJournal of Human Genetics. 2019. PubMed

Genetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson’s Disease. 

Leonard H, Blauwendraat C, Krohn L, Faghri F, Iwaki H, Furgeson G, Day-Williams AG, Stone DJ, International Parkinson’s Disease Genomics Consortium (IPDGC), Singleton AB, Nalls MA and Gan-Or ZGenetic variability and potential effects on clinical trial outcomes: perspectives in Parkinson’s Disease. Journal of Medical Genetics. 2019. PubMedPreprint