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Common and rare variants in HFE are not associated with Parkinson’s disease in Europeans.

Saini P, Bandres-Ciga S, Alcantud JL, Ruz C and Gan-Or ZCommon and rare variants in HFE are not associated with Parkinson’s disease in EuropeansNeurobiology of Aging. 2021. PubMed, Preprint

Analysis of PTRHD1 common and rare variants in European patients with Parkinson’s disease.

Sosero YL, Bandres-Ciga S, Gan-Or Z and Krohn L, on behalf of the International Parkinson’s Disease Genomics Consortium. Analysis of PTRHD1 common and rare variants in European patients with Parkinson’s diseaseNeurobiology of Aging. 2021. PubMed, Preprint

Investigation of Autosomal Genetic Sex Differences in Parkinson’s disease.

Blauwendraat C, Iwaki H, Makarious MB, Bandres-Ciga S, Leonard H, Grenn FP, Lake J, Krohn L, Tan M, Kim JJ, Gibbs JR, Hernandez DG, Ruskey JA, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ, Grosset D, Lesage S, Corvol JC, Brice A, Wood N, Hardy J, Gan-Or Z, Heutink P, Gasser T, Morris H, Noyce AJ, Nalls and Singleton AB. Investigation of Autosomal Genetic Sex Differences in Parkinson’s diseaseAnnals of Neurology. 2021. PubMedPreprint

GCH1 mutations in hereditary spastic paraplegia.

Varghaei P, Yoon G, Estiar MA, Veyron S, Leveille E, Dupre N, Trempe JF, Rouleau GA and Gan-Or ZGCH1 mutations in hereditary spastic paraplegiaClinical Genetics. 2021. PubMedPreprint

Type 2 diabetes as a determinant of Parkinson’s disease risk and progression.

(* equal contribution) Chohan H*, Senkevich K*, Patel RK, Bestwick JP, Jacobs BM, Bandres Ciga S, Gan-Or Z and Noyce AJ. Type 2 diabetes as a determinant of Parkinson’s disease risk and progressionMovement Disorders. 2021. PubMedPreprint

No evidence for a causal relationship between cancers and Parkinson’s disease.

Senkevich K, Bandres-Ciga S, Yu E, Liyanage UE, the International Parkinson Disease Genomics Consortium (IPDGC), Noyce AJ and Gan-Or ZNo evidence for a causal relationship between cancers and Parkinson’s diseaseJournal of Parkinson’s Disease. 2021. PubMedPreprint

Evidence for non-Mendelian inheritance in spastic paraplegia 7.

Estiar MAYu E, Haj Salem I, Ross JP, Mufti K, Akçimen F, Leveille E, Spiegelman D, Ruskey JAAsayesh F, Dagher A, Yoon G, Tarnopolsky M, Boycott KM, Dupre N, Dion PA, Suchowersky O, Trempe JF, Rouleau GA and Gan-Or ZEvidence for non-Mendelian inheritance in spastic paraplegia 7Movement Disorders. 2021. PubMedPreprint

Common X-chromosome variants are associated with Parkinson’s disease risk. 

Le Guen Y, Napolioni V, Belloy ME, Yu EKrohn LRuskey JAGan-Or Z, Kennedy G, Eger SJ and Greicius MD. Common X-chromosome variants are associated with Parkinson’s disease riskAnnals of Neurology. 2021. PubMedPreprint

Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease. 

Manzali SB, Ravona-Springer R, Alkelai A, Yu EGan-Or Z, Ganmore I, Heymann A, Schnaider Beeri M and Greenbaum L. Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease. Neurobiology of Aging. 2021. PubMed

Common variant heritability implicates microglia in Parkinson’s disease pathogenesis.

Andersen MS, Bandres-Ciga S, Reynolds RH, Hardy J, Krohn LGan-Or Z, Holtman IR, International Parkinson’s Disease Genomics Consortium and Pihlstrøm L. Common variant heritability implicates microglia in Parkinson’s disease pathogenesisAnnals of Neurology. 2021. PubMedPreprint