Le Guen Y, Napolioni V, Belloy ME, Yu E, Krohn L, Ruskey JA, Gan-Or Z, Kennedy G, Eger SJ and Greicius MD. Common X-chromosome variants are associated with Parkinson’s disease risk. Annals of Neurology. 2021. PubMed, Preprint
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Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease.
Manzali SB, Ravona-Springer R, Alkelai A, Yu E, Gan-Or Z, Ganmore I, Heymann A, Schnaider Beeri M and Greenbaum L. Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease. Neurobiology of Aging. 2021. PubMed
Common variant heritability implicates microglia in Parkinson’s disease pathogenesis.
Cytokines and Gaucher biomarkers in glucocerebrosidase carriers with and without Parkinson disease.
Galper J, Balwani M, Fahn S, Waters C, Krohn L, Gan-Or Z, Dzamko N and Alcalay RN. Cytokines and Gaucher biomarkers in glucocerebrosidase carriers with and without Parkinson disease. Movement Disorders. 2021. PubMed
Novel associations of BST1 and LAMP3 with rapid eye movement sleep behavior disorder.
Mufti K, Yu E, Rudakou U, Krohn L, Ruskey JA, Asayesh F, Laurent SB, Spiegelman D, Arnulf I, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Dauvilliers Y, Gigli GL, Valente M, Janes F, Bernardini A, Högl B, Stefani A, Holzknecht E, Sonka K, Kemlink D, Oertel W, Janzen A, Plazzi G, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Döring F, Cochen De Cock V, Monaca CC, Heidbreder A, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve B, Trempe JF, Rouleau GA, Postuma RB and Gan-Or Z. Novel associations of BST1 and LAMP3 with rapid eye movement sleep behavior disorder. Neurology. 2021. PubMed, Preprint
Genetic and epidemiological study of adult onset hereditary ataxia and spastic paraplegia in Eastern Quebec.
Haj Salem I, Beaudin M, Stumpf M, Estiar MA, Côté PO, Brunet F, Gamache PL, Rouleau GA, Mourabit-Amari K, Gan-Or Z and Dupré N. Genetic and epidemiological study of adult onset hereditary ataxia and spastic paraplegia in Eastern Quebec. Canadian Journal of Neurological Sciences. 2021. PubMed
Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s disease.
Ramezani M, Ruskey JA, Martens K, Kibreab M, Javer Z, Kathol I, Hammer T, Cheetham J, Leveille E, Martino D, Sarna JR, Gan-Or Z, Pfeffer G, Ismail Z and Monchi O. Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s disease. Frontiers in Neurology. 2021. PubMed
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture.
Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, Hernandez DG, Blauwendraat C, Stone DJ, Eicher J, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, St George-Hyslop P, Londos E, Morgan K, Lashley T, Warner TT, Jaunmuktane Z, Galasko D, Santana I, Tienari PT, Myllykangas L, Oinas M, Cairns NJ, Morris JC, Halliday GM, Van Deerlin VM, Trojanowski JQ, Grassano M, Calvo A, Mora G, Canosa A, Floris G, Bohannan RC, Brett F, Gan-Or Z, Geiger JT, Moore A, May P, Krüger R, Goldstein D, Lopez G, Tayebi N, Sidransky E, Norcliffe-Kaufmann L, Palma JA, Kaufmann H, Shakkottai V, Perkins M, Newell KL, Gasser T, Schulte C, Landi F, Salvi E, Cusi D, Masliah E, Kim RC, Caraway CA, Monuki E, Brunetti M, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Flanagan ME, Mao Q, Bigio EH, Rodríguez-Rodríguez E, Infante J, Lage C, González-Aramburu I, Sanchez-Juan P, Ghetti B, Keith J, Black SE, Masellis M, Rogaeva E, Duyckaerts C, Brice A, Lesage S, Xiromerisiou G, Barrett MJ, Tilley BS, Gentleman S, Logroscino G, Serrano GE, Beach TG, McKeith IG, Thomas AJ, Attems J, Morris CM, Palmer L, Love S, Troakes C, Al-Sarraj S, Hodges AK, Aarsland D, Klein G, Kaiser SM, Woltjer R, Pastor P, Bekris LM, Leverenz J, Besser LM, Kuzma A, Renton AE, Goate A, Bennett DA, Scherzer CR, Morris HR, Ferrari R, Albani D, Pickering-Brown S, Faber K, Kukull W, Morenas-Rodriguez E, Lleó A, Fortea J, Alcolea D, Clarimon J, Nalls MA, Ferrucci L, Resnick SM, Tanaka T, Foroud TM, Graff-Radford NR, Wszolek ZK, Ferman T, Boeve BF, Hardy JA, Topol E, Torkamani A, Singleton AB, Ryten M, Dickson D, Chiò A, Ross OA, Gibbs JR, Dalgard CL, Traynor BJ and Scholz SW. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into the complex genetic architecture. Nature Genetics. 2021. PubMed, Preprint
Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson’s Disease using machine learning.
Ramezani M, Mouches P, Yoon E, Rajashekar D, Ruskey JA, Leveille E, Martens K, Kibreab M, Hammer T, Kathol I, Marouf N, Sarna J, Martino D, Pfeffer G, Gan-Or Z, Forkert ND and Monchi O. Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson’s Disease using machine learning. Scientific Reports. 2021. PubMed
LRRK2 p.M1646T is associated with glucocerebrosidase activity and with Parkinson’s disease.
Sosero YL, Yu E, Krohn L, Rudakou U, Mufti K, Ruskey JA, Asayesh F, Laurent SB, Spiegelman D, Fahn S, Waters C, Sardi SP, International Parkinson Disease Genomics Consortium (IPDGC), Bandres-Ciga S, Alcalay RN, Gan-Or Z and Senkevich K. LRRK2 p.M1646T is associated with glucocerebrosidase activity and with Parkinson’s disease. Neurobiology of Aging. 2021. PubMed, Preprint