Somerville EN, Liu L, Ta M, Iwaki H, Senkevich K, Alcalay RN and Gan-Or Z. Genome-wide association studies identify genetic determinants of synucleinopathy biomarkers. Under review. 2026. Preprint, PubMed

Brain size links neurodevelopment to neurodegeneration in Parkinson’s disease.

Azizi H, Abbasi N, Liu L, Pastor-Bernier A, Tremblay C, Pourmajidian M, Senkevich K, Morys F, Vo A, Moqadam R, Rajimehr R, Yu E, Savadjiev P, Markello RD, Shafiei G, Khatibi N, Jahanshad N, Thompson PM, Poline JB, Gan-Or Z, Misic B, Zeighami Y and Dagher A. Brain size links neurodevelopment to neurodegeneration in Parkinson’s disease. Under review. 2026. Preprint, PubMed

Somerville EN, Liu L, Krohn L, Asayesh F, Ahmad J, Spiegelman D, Teferra M, Tan M, Waters S, Simonet C, Pérez-Carbonell L, Schrag A, Dodet P, Arnulf I, Hu MTM, Ju YE, Montplaisir JY, Gagnon JF, Desautels A, Dauvilliers Y, Aktan-Süzgün M, Ibrahim A, Stefani A, Hogl B, Gaig C, Montini A, Maya G, Iranzo A, Serradell M, Gigli GL, Valente M, Janes F, Bernardini A, Sonka K, Kemlink D, Dusek P, Tamgüney G, Sommerauer M, FigorilliM, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Doring F, Plazzi G, Biscarini F, Antelmi E, Cochen De Cock V, Oertel W, Janzen A, Terzaghi M, Fiamingo G, Heidbreder A, Monaca CC, Ferini-Strambi L, Kulsarova K, Ostrozovicova M, Skorvanek M, Dijkstra F, Viaene M, Bušková J, Abril B, Orso B, Mattioli P, Arnaldi D, Boeve BF, Rouleau GA, Postuma RB, Chung J, Prilutsky D, Atterling Brolin K, Noyce AJ, Ross OA, Blauwendraat C and Gan-Or Z. Genome-wide association study of REM-sleep behaviour disorder identifies new risk loci. Under review. 2026. Preprint, Pubmed

LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli.

MacDougall EJ, Chen CXQ, Deneault E, You Z, Abdian N, Durcan TM, Senkevich K, Gan-Or Z and Fon EA. LRRK2 Kinase Mediates Increased GCase Activity in Microglia in Response to Proinflammatory Stimuli. Under review. 2026. Preprint, PubMed

Post-traumatic stress disorder and REM-sleep behavior disorder: exploring genetic associations and causal links

Ghamgosar Shahkhali M, Liu L, Ghamgosar Shahkhali MH, Yu E, Asayesh F, Ahmad J, Teferra M, Arnulf I, Dodet P, Ju YE, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Ibrahim A, Stefani A, Högl B, Akrtan-Süzgün M, Iranzo A, Serradell M, Montini A, Maya G, Gaig C, Luigi Gigli G, Valente M, Janes F, Bernardini A, Dauvilliers Y, Sonka K, Kemlink D, Dusek P, Sommerauer M, Tamgüney G, Figorilli M, Puligheddu M, Cochen De Cock V, Oertel W, Janzen A, Antelmi E, Mollenhauer B, Trenkwalder C, Sixel-Doring F, Terzaghi M, Fiamingo G, Skorvanek M, Kulcsarova K, Abril B, Charley Monaca C, Ferini-Strambi L, Bušková J, Orso B, Mattioli P, Arnaldi D, Dijkstra F, Viaene M, Boeve BF, Ross OA, Rouleau GA, Neilson LE, Elliott JE, Lim MM, Postuma RB, Gan-Or Z. Post-traumatic stress disorder and REM-sleep behavior disorder: exploring genetic associations and causal links. Under review. 2026. Preprint, PubMed.

Genomic structural equation modeling of impulsivity and risk-taking traits reveals three latent factors distinctly associated with brain structure and development

Shishikura M, Liu L, Yu E, Zhu R, Vilar-Ribó L, Cupertino RB, Palmer AA, Sanchez-Roige S, Vainik U, Morys F, Gan-Or Z, Misic B, Dagher A. Genomic structural equation modeling of impulsivity and risk-taking traits reveals three latent factors distinctly associated with brain structure and development. Under Review. 2026. Preprint, PubMed.

Polygenic scores for disease risk are not associated with clinical outcomes in Parkinson’s disease.

Tan MMX, Iwaki H, Bandres-Ciga S, Sosero Y, Shoai M, Brockmann K, Williams NM, Alcalay RN, Maple-Grødem J, Alves G, Tysnes OB, Auinger P, Eberly S, Heutink P, Simon DK, Kieburtz K, Hardy J, Williams-Gray CH, Grosset DG, Corvol JC, Gan-Or Z, Toft M and Pihlstrøm L. Polygenic scores for disease risk are not associated with clinical outcomes in Parkinson’s disease. Under review. 2026. Preprint, PubMed

Digenic inheritance of mutations in SPG7 and AFG3L2 causes motor neuron and cerebellar disorders.

Estiar MAYu E, Varghaei P, Ross JP, Ashtiani S, Bayne AN, Coarelli G, Timmann D, lockgether T, Beijer D, Mengel D, Coutelier M, Project MinE ALS Sequencing Consortium, Dion PA, Suchowersky O, Ewenczyk C, Goizet C, Van Damme P, Al-Chalabi A, Zuchner S, Synofzik M, Veldink JH, Trempe JF, Durr A, Rouleau GA and Gan-Or ZDigenic inheritance of mutations in SPG7 and AFG3L2 causes motor neuron and cerebellar disorders. Under review. 2026. Preprint, PubMed

Neuroanatomical correlates of polygenic risk for Parkinson Disease.

Abbasi N, Tremblay C, Rajimehr R, Yu E, Markello RD, Shafiei G, Khatibi N, The ENIGMA-Parkinson’s study, Jahanshad N, Thompson PM, Gan-Or Z, Misic B and Dagher A. Neuroanatomical correlates of polygenic risk for Parkinson Disease. Under review. 2026. Preprint, PubMed