Month: October 2024

Yu E, Larivière R, Thomas RA, Liu L, Senkevich K, Rahayel S, Trempe JF, Fon EA and Gan-Or Z. Machine learning nominates the inositol pathway and novel genes in Parkinson’s disease. Brain. Preprint, PubMed

Senkevich K, Pelletier A, Sato C, Keil A, Gan-Or Z, Lang AE, Postuma RB, and Rogaeva E. Epigenetic clock acceleration is linked to earlier onset and phenoconversion age in REM sleep behavior disorder. Annals of Neurology. 2023. Preprint, PubMed

Dorion MF, Yaqubi M, Senkevich K, Kieran NW, MacDonald A, Chen CXQ, Luo W, Wallis A, Shlaifer I, Hall JA, Dudley RWR, Glass IA; Birth Defects Research Laboratory; Stratton JA, Fon EA, Bartels T, Antel JP, Gan-Or Z, Durcan TM, Healy LM. MerTK is a mediator of alpha-synuclein fibril uptake by human microglia. Brain. 2024. Preprint, PubMed

Senkevich K, Beletskaia M, Dworkind A, Yu E, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Greenbaum L, Hassin-Baer S, Nagornov I, Tyurin A, Miliukhina I, Timofeeva A, Emelyanov A, Zakharova E, Alcalay RN, Pchelina A and Gan-Or Z. Association of rare variants in ARSA with Parkinson’s disease. Movement Disorder. 2023. Preprint, PubMed

Yu E, Krohn L, Ruskey JA, Asayesh F, Spiegelman D, Shah Z, Chia R, Arnulf I, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Dauvilliers Y, Gigli GL, Valente M, Janes F, Bernardini A, Hogl B, Stefani A, Ibrahim A, Heidbreder A, Sonka K, Dusek P, Kemlink D, Oertel W, Janzen A, Plazzi G, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Doring F, Cochen De Cock V, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve BF, Rouleau GA, Postuma RB, The International LBD Genomics Consortium, Scholz SW and Gan-Or Z. HLA in isolated REM sleep behavior disorder and Lewy body dementia. Annals of Clinical and Translational Neurology. 2023. Preprint, PubMed

Le Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, Nicolas A, de Rojas I, Leal TP, Miyashita ABellenguez C, Lian MM, Parveen K, Park H, Grenier-Boley B, Naito T, Küçükali F, Talyanski SD, Satake W, Yogeshwar SM, Sempere V, Alvarez V, B Arosio, Belloy ME, Benussi L, Boland A, Borroni B, Bullido MJ, Caffarra P, Clarimon J, Daniele A, Darling D, Debette S, Deleuze JF, Dichgans M, Dufouil C, During E, Düzel E, Galimberti D, Garcia-Ribas G, García-Alberca JM, García-González P, V Giedraitis, Goldhardt O, Graff C, Grünblatt E, Hanon O, Hausner L, Heilmann-Heimbach S, Holstege H, Hort J, Jung YJ, Jürgen D, Kuulasmaa T, Ling L, van der Lugt A, Masullo C, Mecocci P, Mehrabian S, de Mendonça A, Mercè B, Mir P, Moebus S, Moreno F, Nacmias B, Nicolas G, Nordestgaard BG, Oksenberg J, G Papenberg, Parnetti L, Pasquier F, Pastor P, O Peters, Pijnenburg YAL, Piñol-Ripoll G, Popp J, Porcel LM, Puerta R, Pérez-Tur J, I Rainero, Ramakers I, Real LM, Riedel-Heller S, Rodriguez-Rodriguez E, Royo JL, Rujescu D, Scarmeas N, Scheltens P, Scherbaum N, Schneider A, Seripa D, Solfrizzi V, Spalletta G, Squassina A, van Swieten J, Sánchez-Valle R, Tegos T, Tremolizzo L, Vyhnalek M, Verhey F, Wiltfang J, Zhang J, Williams J, Amouyel P, Jessen F, Kehoe P, Andreassen O, Van Duin C, Tsolaki M, Sánchez-Juan P, Frikke-Schmidt R, Sleegers K, Toda T, Ingelsson M, Okada Y, Rossi G, Hiltunen M, Gim J, Sims R, Foo JN, van der Flier W, Ikeuchi T, Ramirez A, Matta I, Ruiz A, Gan-Or Z, Lambert JC, Greicius MD and Mignot E. Protective association of HLA-DRB1*04 subtypes in neurodegenerative diseases implicates acetylated Tau PHF6 sequences. Proceedings of the National Academy of Sciences (PNAS). 2023. Preprint, PubMed

Somerville EN, Krohn L, Yu E, Rudakoua U, Senkevich K, Ruskey JA, Asayesh F, Ahmad J, Spiegelman D, Dauvilliers Y, Arnulf A, Hu MTM, Montplaisir JY, Gagnon JF, Desautel A, Ibrahim A, Stefani A, Hogl B, Gigli GL, Valente M, Janes F, Bernardini A, Duseko P, Sonka K, Kemlink D, Plazzi G, Antelmi E, Biscarini F, Mollenhauert B, Trenkwalder C, Sixel-Doring F, Figorilli M, Puligheddu M, Cochen De Cock V, Ferini-Strambi L, Heibreder A, Monaca CC, Abril B, Dijkstra F, Viaene M, Boeve BF, Postuma RB, Rouleaua GA and Gan-Or Z. NPC1 variants are not associated with Parkinson’s disease, REM-sleep behaviour disorder or Dementia with Lewy bodies in European cohorts. Neurobiology of Aging. 2023. Preprint, PubMed

Senkevich K, Alipour P, Chernyavskaya E, Yu E, Noyce AJ and Gan-Or Z. Potential protective link between type I diabetes and Parkinson’s disease risk and progression. Movement Disorders. 2023. Preprint, PubMed

Sosero YL and Gan-Or Z. LRRK2 and Parkinson’s disease: from genetics to targeted therapy. Annals of Clinical and Translationa Neurology. 2023. PubMed

Jerez PA, Alcantud JL, de los Reyes-Ramírez L, Moore A, Ruz C, Vives Montero F, Rodriguez-Losada N, Saini P, Gan-Or Z, Alvarado C, Makarious MB, Billingsley KJ, Blauwendraat C, Noyce AJ, Singleton AB, Duran R and Bandres-Ciga S. Exploring the Genetic and Genomic Connection Underlying Neurodegeneration with Brain Iron Accumulation and the Risk for Parkinson’s Disease. npj Parkinson’s Disease. 2023. Preprint, PubMed