Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, del Cid Pellitero, Chen CXC, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z (co-corresponding author) and Fon EA. Parkinson’s risk gene CTSB promotes α-synuclein clearance and lysosome function in dopamine neurons. Mol Neurodegener. 2024. Preprint, PubMed
Month: October 2024
Parkinson’s risk gene CTSB promotes α-synuclein clearance and lysosome function in dopamine neurons. Under review. 2023
Jones-Tabah J, He K, Senkevich K, Karpilovsky N, Deyab G, Cousineau Y, Nikanorova D, Goldsmith T, del Cid Pellitero, Chen CXC, Luo W, You Z, Abdian N, Pietrantonio I, Goiran T, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z (co-corresponding author) and Fon EA. Parkinson’s risk gene CTSB promotes α-synuclein clearance and lysosome function in dopamine neurons. Under review. 2023. Preprint, PubMed
Are LRRK2 p.G2019S or GBA1 variants associated with long-term outcomes of deep brain stimulation for Parkinson’s disease?
Anis S, Goldberg T, Shvueli E, Kozlov Y, Redlich Y, Lavi N, Lavie I, Sosero YL, Gan-Or Z, Ungar L, Zibly Z, Greenbaum L, Fay-Karmon T and Hassin-Baer S. Are LRRK2 p.G2019S or GBA1 variants associated with long-term outcomes of deep brain stimulation for Parkinson’s disease? Parkinsonism Relat Disord. 2024. PubMed
Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium
Elliott J, Ligman B, Bryant-Ekstrand M, Keil A, Powers K, Olivio C, Neilson L, Postuma R, Pelletier A, Gagnon JF, Gan-Or Z, Yu E, Liu L, St. Louis E, Forsberg L, Fields J, Huddleston D, Bliwise D, Avidan A, Howell M, Schenck C, McLeland J, Criswell S, Videnovic A, During E, Miglis M, Shprecher D, Lee-Iannotti J, Boeve B, Ju YE and Lim M. Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium. Sleep. 2024. PubMed
Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium.
Elliott J, Ligman B, Bryant-Ekstrand M, Keil A, Powers K, Olivio C, Neilson L, Postuma R, Pelletier A, Gagnon JF, Gan-Or Z, Yu E, Liu L, St. Louis E, Forsberg L, Fields J, Huddleston D, Bliwise D, Avidan A, Howell M, Schenck C, McLeland J, Criswell S, Videnovic A, During E, Miglis M, Shprecher D, Lee-Iannotti J, Boeve B, Ju YE and Lim M. Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium. Sleep. 2024. PubMed
Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson′s disease.
Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia.
Sosero YL, Ferwerda B, Tocino MTP, Belloso DR, Gomez-Garre P, Faouzi J, Pavelka L, Marques TM, Gomes CPC, Kolodkin A, May P, Milanowski LM, Wszolek ZK, Uitti RJ, Heutink P, van Hilten J, Simon DK, Eberly S, Fernandez IA, Krohn L, Yu E, Freeman K, Rudakou U, Ruskey JA, Asayesh F, Menendez M, Pastor P, Ross O, Kruger R, Corvol JC, Koks S, Mir P, de Bie RMA, Iwaki H and Gan-Or Z. Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia. Movement Disorders. 2024. Preprint, PubMed
Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease.
Menon PJ, Sambin S, Criniere-Boizet B, Courtin T, Tesson C, Casse F, Ferrien M, Mariani LL, Carvalho S, Lejeune FX, Rebbah S, Martet G, Houot M, Lanore A, Mangone G, Roze E, Vidailhet M, Aasly J, Gan-Or Z, Yu E, Dauvilliers Y, Zimprich A, Tomantschger V, Pirker W, Álvarez I, Pastor P, Di Fonzo A, Bhatia KP, Magrinelli F, Houlden H, Real R, Quattrone A, Limousin P, Korlipara P, Foltynie T, Grosset D, Williams N, Narendra D, Lin HP, Jovanovic C, Svetel M, Lynch T, Gallagher A, Vandenberghe W, Gasser T, Brockmann K, Morris HR, Borsche M, Klein C, Corti O, Brice A, Lesage S and Corvol JC. Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease. npj Parkinson’s Disease. 2024. Preprint, PubMed
Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease.
Sosero YL, Heilbron K, Fontanillas P, Norcliffe-Kaufmann L, Yu E, Rudakou U, Ruskey JA, Freeman K, Asayesh F, Brolin K, Swanberg M, Morris HR, Wu L, Real R, Pihlstrøm L, Tan M, Gasser T, Brockmann K, Liu H, Hu MTM, Grosset DG, Lewis SJG, Kwok JB, Pastor P, Alvarez I, Skorvanek M, Lackova A, Ostrozovicova M, Rizig M, 23andMe Research Team, The International Parkinson’s Disease Genomics Consortium, Krohn L and Gan-Or Z. Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease. Under review. 2024. Preprint, PubMed
Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease
Senkevich K, Bandres-Ciga S, Cisterna-García A, Yu E, Bustos BI, Krohn L, Lubbe SJ, Botía JA, the International Parkinson’s Disease Genomics Consortium (IPDGC) and Gan-Or Z. Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease. Under review. Preprint, PubMed