Type 2 diabetes as a determinant of Parkinson’s disease risk and progression.

(* equal contribution) Chohan H*, Senkevich K*, Patel RK, Bestwick JP, Jacobs BM, Bandres Ciga S, Gan-Or Z and Noyce AJ. Type 2 diabetes as a determinant of Parkinson’s disease risk and progressionMovement Disorders. 2021. PubMedPreprint

No evidence for a causal relationship between cancers and Parkinson’s disease.

Senkevich K, Bandres-Ciga S, Yu E, Liyanage UE, the International Parkinson Disease Genomics Consortium (IPDGC), Noyce AJ and Gan-Or ZNo evidence for a causal relationship between cancers and Parkinson’s diseaseJournal of Parkinson’s Disease. 2021. PubMedPreprint

Evidence for non-Mendelian inheritance in spastic paraplegia 7.

Estiar MAYu E, Haj Salem I, Ross JP, Mufti K, Akçimen F, Leveille E, Spiegelman D, Ruskey JAAsayesh F, Dagher A, Yoon G, Tarnopolsky M, Boycott KM, Dupre N, Dion PA, Suchowersky O, Trempe JF, Rouleau GA and Gan-Or ZEvidence for non-Mendelian inheritance in spastic paraplegia 7Movement Disorders. 2021. PubMedPreprint

Common X-chromosome variants are associated with Parkinson’s disease risk. 

Le Guen Y, Napolioni V, Belloy ME, Yu EKrohn LRuskey JAGan-Or Z, Kennedy G, Eger SJ and Greicius MD. Common X-chromosome variants are associated with Parkinson’s disease riskAnnals of Neurology. 2021. PubMedPreprint

Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease. 

Manzali SB, Ravona-Springer R, Alkelai A, Yu EGan-Or Z, Ganmore I, Heymann A, Schnaider Beeri M and Greenbaum L. Association of the CD2AP locus with cognitive functioning among middle aged individuals with a family history of Alzheimer’s disease. Neurobiology of Aging. 2021. PubMed

Common variant heritability implicates microglia in Parkinson’s disease pathogenesis.

Andersen MS, Bandres-Ciga S, Reynolds RH, Hardy J, Krohn LGan-Or Z, Holtman IR, International Parkinson’s Disease Genomics Consortium and Pihlstrøm L. Common variant heritability implicates microglia in Parkinson’s disease pathogenesisAnnals of Neurology. 2021. PubMedPreprint

Cytokines and Gaucher biomarkers in glucocerebrosidase carriers with and without Parkinson disease.

Galper J, Balwani M, Fahn S, Waters C, Krohn LGan-Or Z, Dzamko N and Alcalay RN. Cytokines and Gaucher biomarkers in glucocerebrosidase carriers with and without Parkinson diseaseMovement Disorders. 2021. PubMed

Novel associations of BST1 and LAMP3 with rapid eye movement sleep behavior disorder.

Mufti KYu ERudakou UKrohn LRuskey JAAsayesh F, Laurent SB, Spiegelman D, Arnulf I, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Dauvilliers Y, Gigli GL, Valente M, Janes F, Bernardini A, Högl B, Stefani A, Holzknecht E, Sonka K, Kemlink D, Oertel W, Janzen A, Plazzi G, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Döring F, Cochen De Cock V, Monaca CC, Heidbreder A, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve B, Trempe JF, Rouleau GA, Postuma RB and Gan-Or ZNovel associations of BST1 and LAMP3 with rapid eye movement sleep behavior disorderNeurology. 2021. PubMedPreprint

Genetic and epidemiological study of adult onset hereditary ataxia and spastic paraplegia in Eastern Quebec.

Haj Salem I, Beaudin M, Stumpf M, Estiar MA, Côté PO, Brunet F, Gamache PL, Rouleau GA, Mourabit-Amari K, Gan-Or Z and Dupré N. Genetic and epidemiological study of adult onset hereditary ataxia and spastic paraplegia in Eastern Quebec. Canadian Journal of Neurological Sciences. 2021. PubMed

Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s disease.

Ramezani M, Ruskey JA, Martens K, Kibreab M, Javer Z, Kathol I, Hammer T, Cheetham J, Leveille E, Martino D, Sarna JR, Gan-Or Z, Pfeffer G, Ismail Z and Monchi O. Association between BDNF Val66Met polymorphism and mild behavioral impairment in patients with Parkinson’s disease. Frontiers in Neurology. 2021. PubMed