Elliott J, Ligman B, Bryant-Ekstrand M, Keil A, Powers K, Olivio C, Neilson L, Postuma R, Pelletier A, Gagnon JF, Gan-Or Z, Yu E, Liu L, St. Louis E, Forsberg L, Fields J, Huddleston D, Bliwise D, Avidan A, Howell M, Schenck C, McLeland J, Criswell S, Videnovic A, During E, Miglis M, Shprecher D, Lee-Iannotti J, Boeve B, Ju YE and Lim M. Comorbid neurotrauma increases synucleinopathy-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium. Sleep. 2024. PubMed
Month: October 2024
Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson′s disease.
Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia.
Sosero YL, Ferwerda B, Tocino MTP, Belloso DR, Gomez-Garre P, Faouzi J, Pavelka L, Marques TM, Gomes CPC, Kolodkin A, May P, Milanowski LM, Wszolek ZK, Uitti RJ, Heutink P, van Hilten J, Simon DK, Eberly S, Fernandez IA, Krohn L, Yu E, Freeman K, Rudakou U, Ruskey JA, Asayesh F, Menendez M, Pastor P, Ross O, Kruger R, Corvol JC, Koks S, Mir P, de Bie RMA, Iwaki H and Gan-Or Z. Dopamine pathway and Parkinson’s risk variants are associated with levodopa-induced dyskinesia. Movement Disorders. 2024. Preprint, PubMed
Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease.
Menon PJ, Sambin S, Criniere-Boizet B, Courtin T, Tesson C, Casse F, Ferrien M, Mariani LL, Carvalho S, Lejeune FX, Rebbah S, Martet G, Houot M, Lanore A, Mangone G, Roze E, Vidailhet M, Aasly J, Gan-Or Z, Yu E, Dauvilliers Y, Zimprich A, Tomantschger V, Pirker W, Álvarez I, Pastor P, Di Fonzo A, Bhatia KP, Magrinelli F, Houlden H, Real R, Quattrone A, Limousin P, Korlipara P, Foltynie T, Grosset D, Williams N, Narendra D, Lin HP, Jovanovic C, Svetel M, Lynch T, Gallagher A, Vandenberghe W, Gasser T, Brockmann K, Morris HR, Borsche M, Klein C, Corti O, Brice A, Lesage S and Corvol JC. Genotype-Phenotype correlations in PRKN-associated Parkinson’s disease. npj Parkinson’s Disease. 2024. Preprint, PubMed
Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease.
Sosero YL, Heilbron K, Fontanillas P, Norcliffe-Kaufmann L, Yu E, Rudakou U, Ruskey JA, Freeman K, Asayesh F, Brolin K, Swanberg M, Morris HR, Wu L, Real R, Pihlstrøm L, Tan M, Gasser T, Brockmann K, Liu H, Hu MTM, Grosset DG, Lewis SJG, Kwok JB, Pastor P, Alvarez I, Skorvanek M, Lackova A, Ostrozovicova M, Rizig M, 23andMe Research Team, The International Parkinson’s Disease Genomics Consortium, Krohn L and Gan-Or Z. Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease. Under review. 2024. Preprint, PubMed
Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease
Senkevich K, Bandres-Ciga S, Cisterna-García A, Yu E, Bustos BI, Krohn L, Lubbe SJ, Botía JA, the International Parkinson’s Disease Genomics Consortium (IPDGC) and Gan-Or Z. Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease. Under review. Preprint, PubMed
APOE – e4 is not associated with pure-tone hearing thresholds, visual acuity or cognition, cross-sectionally or over 3 years of follow up in the Canadian Longitudinal Study on Aging.
Mick P, Kabir R, Karunatilake M, Kathleen Pichora-Fuller M, Young TL, Sosero Y, Gan-Or Z, Wittich W, Phillips NA. APOE – e4 is not associated with pure-tone hearing thresholds, visual acuity or cognition, cross-sectionally or over 3 years of follow up in the Canadian Longitudinal Study on Aging. Neurobiology of Aging. 2024. Preprint, PubMed
Autosomal dominant Parkinson’s disease caused by SNCA p.E46K mutation in a family with Russian ancestry.
Senkevich K, Miliukhina I, Zhuravlev A, Shumilova M, Beletskaia M, Skvortsova T, Yu E, Ahmad J, Asayesh F, Gan-Or Z, Emelyanov A and Pchelina S. Autosomal dominant Parkinson’s disease caused by SNCA p.E46K mutation in a family with Russian ancestry. Movement Disorders. 2024. PubMed
Neuroanatomical correlates of polygenic risk for Parkinson Disease.
Abbasi N, Tremblay C, Rajimehr R, Yu E, Markello RD, Shafiei G, Khatibi N, The ENIGMA-Parkinson’s study, Jahanshad N, Thompson PM, Gan-Or Z, Misic B and Dagher A. Neuroanatomical correlates of polygenic risk for Parkinson Disease. Under review. Preprint, PubMed
Lessons and future directions for GBA1 targeting therapies.
Gan-Or Z. Lessons and future directions for GBA1 targeting therapies. Lancet Neurology. 2023. PubMed